Photocatalyzed Reactions

Photocatalysis uses light and catalysts to enable green, radical-based synthesis under mild conditions. TBADT activates inert C–H bonds, and ongoing research targets electron transfer and visible-light photocatalysts.

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Reactions of Photogenerated Aryl Cations

Photoheterolysis enables mild, metal-free generation of aryl cations for forming aryl-carbon bonds. This versatile method yields bioactive compounds and offers green alternatives to traditional arylation strategies.

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Scale-up of Photochemical Syntheses

Photochemical reactions remain underutilized industrially due to scalability challenges. Our lab is optimizing protocols for greener, large-scale synthesis using flow systems, sunlight, LEDs, and microreactors to enhance efficiency and sustainability.

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Preparation of Potential Chemotherapeutics Activated by Light

Potent DNA-cleaving DHTs are generated photochemically from stable benzyl precursors via phenyl cations, offering a practical, customizable alternative to enyne-allene cyclization for therapeutic applications.

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Aromatic Sulfonates and Phosphates as PhotoAcid Generators (PAGs)

Efficient acid photorelease from aryl halides, sulfonates, and phosphates enables tunable photoacid generators (PAGs), advancing high-resolution photoresist design for microelectronics and nanofabrication.

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